The safety of NEXGARD SPECTRA Chewable Tablets has not been evaluated in breeding, pregnant or lactating dogs. Nexgard Ingredients And Directions. Commercial chewable tablets of different strength were combined to deliver doses as close as possible to the minimum effective dose of 2.5mg afoxolaner plus 0.5mg milbemycin oxime per kg body weight. Administer appropriate dosage per month based on your pet's weight. NexGard Spectra® 11 ad us. The most frequently reported adverse reaction was vomiting. Additionally, there is also Nexgard Spectra, which protects against fleas, ticks, mites, heartworms, and intestinal worms. Should your dog vomit within 2 hours of the dose having been administered, then redose again giving another full dose. veterinary surgeon, veterinary nurse or veterinary student). Background: A multi-centre field trial was conducted to evaluate the efficacy of afoxolaner based chewables (NexGard® or NexGard Spectra®) for the treatment of generalised demodicosis caused by Demodex canis in dogs under field conditions in France, Italy and Poland. Nexgard Spectra is an advanced treatment for controlling fleas and ticks on dogs. Because Nexgard help stop these seizures, this is why some people think that Nexgard can cause seizures in dogs. 9 mg/ 2 mg NEXGARD SPECTRA 19 mg/ 4 mg NEXGARD SPECTRA 38 mg/ 8 mg NEXGARD SPECTRA 75 mg/ 15 mg NEXGARD SPECTRA 150 mg/ 30 mg 2–3,5 … Treatment may begin at any time of the year, and should continue the entire year without interruption. Use with caution in dogs with a history of seizures or neurologic disorders. Every effort has been made to ensure the accuracy of the NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS) information published above. Intestinal Nematodes Treatment and Prevention: Dogs may be exposed to and can become infected with hookworms, roundworms and whipworms throughout the year. Hypersensitivity reactions manifested by laboured respiration, lethargy, vomiting and salivation have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. 1 . To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. NexGard (afoxolaner) is for use in dogs only. Dosage of NexGard Spectra. It is recommended, in accordance with the American Heartworm Society that: - Infected dogs should be treated with labeled adulticides and microfilaricides (if microfilaria are present) as soon after diagnosis as medically practical. The efficacy of NexGard ® and NexGard Spectra ® against sarcoptic mange in dogs was evaluated in a clinical field study. 100% of owners said NexGard SPECTRA was easy to give to their dog. The oral tablet is also useful for the treatment of gut worms including roundworms, hookworms and whipworms. Product Compare (0) Show: Sort By: Nexgard Spectra Orange Extra Small Dog. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Nexgard chien 25 50 kg. The dog remained enrolled and completed the study. It might result in under dosing. Nexgard Spectra is a product chosen by most of the pet parents when it comes to the treatment of fleas and ticks. For ticks, Dermacentor variabilis and Ixodes scapularis >90% are killed within 48 hours and for Amblyomma americanum >90% are killed within 72 hours. NexGard (afoxolaner) is for use in dogs only.The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Treatment may begin at any time of the year, and should continue the entire year without interruption. 11. Nexgard Spectra is a new once a month, chewable tablet for the effective control of fleas, ticks, heartworm and intestinal worms for dogs and puppies. Nexgard Spectra combines two active ingredients (Afoxolaner and Milbemycin Oxime) for protection against the most common internal and external parasites of dogs. NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. A total of 106 dogs were screened at eight sites in Portugal and Germany. List. Effets indésirables. NexGard Spectra is a monthly chewable treatment for dogs made with soy proteins and braised beef flavorings that dogs love. Buy Nexgard Spectra . If a dose is missed, administer NEXGARD SPECTRA and resume an every 30 day dosing regimen. If your dog’s heartworm prevention has lapsed, speak to your veterinarian. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated.Use with caution in dogs with a … - Annual testing of all dogs for heartworm should be done. Copyright © 2021 Animalytix LLC. For ease of dosing, NexGard SPECTRA can be given with or without food. Also, NexGard is safe for use with small dogs weighing at least 4 pounds. In the clinical field study there were 2 dogs in the NEXGARD SPECTRA group and one dog in the active control group that had diarrhea associated with Clostridium perfringens infection. Précautions particulières à prendre par la personne qui administre le médicament aux animaux : - Ce produit peut causer des troubles gastro-intestinaux en cas d’ingestion. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using these data. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. Benefits of NexGard Spectra. To establish a treatment routine, it is recommended that the same day or date be used each month. NexGard Spectra est administré une fois par mois à croquer, avec la dose exacte en fonction du poids corporel de votre chien. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. The safety of NEXGARD SPECTRA in puppies less than 8 weeks of age has not been evaluated. The dog remained enrolled and completed the study. Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. Cautions . Nex Gard Dosage for Dogs and Puppies (over 8 weeks of age): NexGard for dogs 4-10 lbs (Very Small Dogs 2-4 kg) (Afoxolaner 11.3 mg): Administer one chew per month; NexGard for dogs 10-24 lbs (Small Dogs 4-10 kg) (Afoxolaner 28.3 mg): Administer one chew per month Nexgard spectra chien 4 10 kg. NexGard Spectra Extra Large Dogs Chewable Tablets for dogs 3pk. NexGard Spectra goes an extra step by treating internal parasites as well with the same oral dose, so it’s worth considering for any dog owner. NexGard SPECTRA is a highly palatable chew that is readily consumed by dogs when offered as a treat. La dose recommandée doit être strictement respectée chez les colleys ou les races apparentées. Si une dose est manquée, administrer NexGard et reprendre un calendrier de dosage mensuel. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Each strength is available in colour-coded packages of 3, 6 or 12 chewable tablets. Le vétérinaire m’a donné un comprimé pour chien de 10 à 30$ je trouve pas où m’inscrire merci j’ai déjà utilisé le … NexGard is a monthly soft chewable that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of American Dog Tick infestations (Dermacentor variabilis) in dogs. In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. For prevention of flea infestation, NEXGARD SPECTRA should be administered ideally just before fleas become active. Nexgard Spectra delivers the most complete protection from fleas, ticks, heartworm and intestinal worms available, in one monthly chew. Nexgard kills all adult fleas within 24 hours before they can lay eggs. The oral tablet is also useful for the treatment of gut worms including roundworms, hookworms and whipworms. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. There were no clinically-relevant effects related to treatment on physical examination, body weight, food consumption, clinical pathology (hematology, clinical chemistries, or coagulation tests), gross pathology, histopathology or organ weights. Select one or more newsletters to continue. Administration of NEXGARD SPECTRA should coincide with the time of year the ticks are active. It’s the most complete protection available in just one chew, and best of all your dog will love it. These laboratory studies used US isolates obtained from Georgia (Duke and Pepper strains) and Michigan (Michigan strain). Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. In two well-controlled laboratory studies, NEXGARD SPECTRA was 69% effective against heartworm infections induced with the US JYD-34 strain when administered for 6 consecutive monthly doses. 1 > 3,5 – 7,5 . If a dose is missed, administer NEXGARD SPECTRA and resume an every 30 day dosing regimen. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. - the treatment and control of intestinal nematode infections caused by adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis). Afoxolaner is a member of the isoxazoline class. In two separate, well-controlled laboratory studies, NEXGARD SPECTRA was effective at preventing Borrelia burgdorferi infections after dogs were infested, at room temperature, with adult Ixodes scapularis vector ticks 28 days post-treatment. Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. NexGard Spectra Chewables is obtained after a month, secure for all Breeds and dogs from 8 weeks old and 2kg or more. For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Merial at 1-888-637-4251 or www.nexgardfordogs.com. Can be administered with or without food. Nb et dosage de comprimé de Nexgard Spectra . At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30 days. NexGard Spectra Chewable Tablets are chewable beef flavoured tablets for dogs used for the treatment of flea and tick infestations as well as the prevention of heartworm disease and treatment of … Clostridium perfringens infection and gastritis with hypomotility were detected and were not determined to be treatment-related. What Is NexGard. Veterinarian's Assistant: I'm sorry to hear that. DIN 02473364 (9.4 mg/1.9 mg), 02473372 (18.8 mg/3.8 mg), 02473380 (37.5 mg/7.5 mg), 02473399 (75 mg/15 mg), 02473402 (150 mg/30 mg), Boehringer Ingelheim Animal Health Canada Inc., 5180 South Service Road, Burlington ON L7L 5H4. If treatment is delayed, whether by a few days or many, immediate treatment with NEXGARD SPECTRA and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms. If a dose is missed, administer NexGard and resume a monthly dosing schedule. Some dogs will have seizures when they are exposed to certain stimuli. NexGard Spectra® is a prescription only medicine. To be effective NEXGARD SPECTRA should be administered every 30 days. tick and the Lone Star tick). Dogs in the control group were sham-dosed. One female dog (1x dose group) had sporadic emesis and diarrhea with blood and slightly increased body temperature and decreased white blood cell count. ®NexGard is a registered trademark, and ™FRONTLINE VET LABS is a trademark, of Merial. You've found us the hard way, don't let the luck slip away, order your Pet Meds right away! Le produit doit être administré à une dose de 2,7–6,9 mg/kg de poids corporel : - si le poids du chien est de 2–4 kg: 1 comprimé à croquer NexGard ® 11 mg. - si le poids du chien est de >4–10 kg: 1 comprimé à croquer NexGard ® 28 mg. - si le poids du chien est de >10–25 kg: 1 comprimé à croquer NexGard ® 68 mg. 2 – 3,5 . Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. Prolonged Afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Each chewable size is available in color-coded packages of 1, 3 or 6 beef-flavored chewables. Nexgard Spectra Chewable Tablets are for the treatment of flea and tick infestations in dogs when the concurrent prevention of heartworm disease and/or treatment of gastrointestinal nematode infestations is indicated. The tasty chew also treats and prevents gastrointestinal nematode infestations. NexGard Spectra is suitable for use with dogs and puppies from 8 weeks of age, with a minimum body weight of 4.5 lbs (2 kg). Nexgard Spectra e n’a entraîné aucun effet indésirable grave. The new soft, beef flavored chew kills fleas and ticks, now with the added benefit of treatment for heartworms, roundworms, hookworms, and whipworms. In two separate, well-controlled laboratory studies, NexGard was effective at preventing Borrelia burgdorferi infections after dogs were infested with Ixodes scapularis vector ticks 28 days post-treatment. These reactions are presumably caused by the release of protein from dead or dying microfilariae. Afoxolaner and Milbemycin Oxime Chewable Tablets. Available for Android and iOS devices. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. The occurrence of vomiting was generally self-limiting and of short duration. Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. 95% of Bush ticks were killed by 72 hours. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). NexGard is a monthly soft chewable that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of American Dog Tick infestations (Dermacentor variabilis) in dogs.. NexGard kills 3 common types of ticks (the American dog tick, the black-legged ??Deer?? So NexGard decreases the risk of a deadly tick-borne disease. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or rejected. NexGard for Dogs - 60 - 120 lbs - RED - 3 tablets. NexGard kills 3 common types of ticks (the American dog tick, the black-legged ?Deer? NEXGARD SPECTRA™ is a trademark of the Boehringer Ingelheim Group. It gives protection against fleas for up to five weeks and controls ticks for up to four weeks. Is he going to be OK, or do I need to take him to an emergency vet? Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. There are no known contraindications for the use of NexGard. Use with caution in dogs with a history of seizures or neurologic disorders. 1Number of dogs in the afoxolaner treatment group with the identified abnormality. In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. Clinical observations included diarrhea, diarrhea with blood and vomiting which were observed sporadically across all groups, including the controls. Milbemycin Oxime acts by disrupting the glutamate neuro-transmission in invertebrates. In three well-controlled laboratory studies, NEXGARD SPECTRA was 100% effective against induced heartworm infections when administered for 6 consecutive monthly doses after infection. Dosage. Copyright © 2021 Animalytix LLC. Data from the laboratory studies demonstrate that NEXGARD SPECTRA kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the initial treatment of existing flea infestations. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. 1306. In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. Can a Nexgard spectra chew be split so I can dose more than one dog? 9/2mg . tick and the Lone Star tick). A fixed-combination chewable tablet incorporating afoxolaner plus milbemycin oxime (NexGard Spectra ®, Merial) was tested in purpose-bred Beagle dogs for efficacy against adult Ancylostoma ceylanicum hookworms.Sixteen dogs were inoculated each by oral administration of approximately 500 infective larvae of A. ceylanicum. 10. Use with caution in dogs with a history of seizures or neurologic disorders (see Adverse Reactions and Post-Approval Experience). Your dog’s first dose of NexGard SPECTRA must be administered on, or before, the next due date of the current heartworm preventative. The selective toxicity of afoxolaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines’ GABA receptors versus mammalian GABA receptors. Ticks: In well-controlled laboratory studies, NEXGARD SPECTRA demonstrated > 90% effectiveness for 30 days against Amblyomma americanum 72 hours post-infestation. This leads to hyperpolarisation of the neuromuscular membrane resulting in paralysis and death of the parasites. - Uninfected dogs should be maintained on preventives year round to protect them from heartworm disease. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Prolonged afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Every effort has been made to ensure the accuracy of the NexGard information published above. Dosage. Remove only one chewable at a time from the foil-backed blister card. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Both NexGard® and NexGard Spectra® are now approved for the treatment of the cutaneous diseases demodicosis (caused by the Demodex canis mite) as well as sarcoptic mange (caused by the Sarcoptes scabiei var. Afoxolaner is the active principle of the veterinary medicinal products NexGard (alone) and Nexgard Spectra (in combination with milbemycin oxime). Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. NexGard Spectra has not been evaluated as safe for use on pregnant or lactating dogs. NEXGARD SPECTRA ® 9 mg/2 mg ... La dose recommandée doit être strictement respectée chez les colleys ou les races apparentées. Context Menu. It comes in a monthly dose and is flavored to make it more palatable. The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. NexGard Spectra for X-Small Dogs - 4 - 8 lbs - ORANGE - 3 tablets. The table below presents the most common adverse reactions during the study. Ne pas utiliser en cas d’hypersensibilité aux substances actives ou à l’un des excipients. The most frequently reported adverse reaction in the NEXGARD SPECTRA and active control groups was vomiting. The dog recovered with treatment. Nexgard Spectra est utilisé dans le traitement des infestations par les puces et les tiques et/ou des vers intestinaux chez les chiens. It can be given to the puppies more than 8 weeks of age and weighing more than 2 kgs. Calendrier de dosage. 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